Inflammatory breast cancer, a more rare and much more lethal form of cancer that has as its primary sign redness, sometimes without any lump, represents up to 3 percent of breast cancer diagnoses in the United States. But it is a particularly aggressive form of the disease that can be fatal in a few months if untreated.
“This disease needs immediate diagnosis to save lives. The mortality is high, but there’s a lot that can be done. You can live 10 to 20 years or longer with treatment,” says Dr. Sofia Merajver, co-director of the Breast Oncology Program at the Comprehensive Cancer Center.
Merajver, internationally known for her research into this rare type of cancer, will direct a new clinic at the center specifically for inflammatory breast cancer. The clinic will allow women to receive state-of-the-art care. It is one of only a handful of sites in the country to specialize in inflammatory breast cancer, and the only site in Michigan.
Inflammatory breast cancer is a very aggressive type of the disease in which cancerous cells move rapidly throughout the breast and clog the lymph vessels in the skin, causing the breast to look swollen, red, itchy or inflamed. It’s often mistaken for a rash or infection and many women are initially treated with antibiotics or steroids.
“There are many options for treating this disease. In many cases, the treatment is going to be on-and-off for life. There will be times of remission, but this is a serious disease that has a high chance of recurring,” says Merajver, a professor of internal medicine at the Medical School.
Because the disease tends to come back, it’s important to have continuity of care and for doctors to know what treatments have already been tried or have failed. The new clinic will allow for this type of record-keeping, even if patients are treated by their community physicians or at other centers.
“The U-M Inflammatory Breast Cancer Clinic will be a clearinghouse where we can provide tertiary care and advice,” Merajver says. She currently consults with oncologists from around the world about patients with inflammatory breast cancer and expects to continue this practice.
U-M already treats women with inflammatory breast cancer, but the new dedicated clinic will ensure coordinated care, as well as more research opportunities. The Cancer Center expects to see about 80 patients per year at this clinic. About a quarter of those patients will come only for consultations and will eventually be treated in their community; the remainder will receive treatment at U-M.
About inflammatory breast cancer
• Represents 3-6 percent of the 180,000 women diagnosed with breast cancer each year
• With treatment, 20-40 percent of patients survive 10 years. This is up from 5-10 percent 20 years ago
• Characterized by redness, warmth or an orange-skin appearance on the skin of the breast. A persistent red breast should be biopsied promptly
• May or may not cause a lump or mass.
• Treatment includes aggressive chemotherapy, followed by surgery and radiation therapy
For an appointment or questions about inflammatory breast cancer, call the Cancer AnswerLine at (800) 865-1125.
